TRANSITION Oral is the foundational perimenopause protocol for women whose bodies are producing less estrogen and progesterone every month. Real hormone replacement, prescribed by physicians who actually listen — plus DSIP, a sleep peptide that addresses the night-sweat sleep disruption HRT alone doesn't fully resolve. If you've been told your symptoms are "normal" or offered an SSRI instead of hormones, this is what you were supposed to be offered.