Oral · Nightly

Progesterone (oral SR)

Monthly Plan
From $39 /first month
Quarterly Plan
$189 quarterly

FREE + EASY cancellation anytime for any reason

• Supports progesterone receptor signaling in uterine tissue
• Designed to complement estradiol in a balanced HRT protocol
• May help support sleep-related neurosteroid pathways
• Targets receptors involved in endometrial tissue regulation
• Delivered by licensed physicians as part of guided HRT

Monthly Plan
From $39 /first month
Quarterly Plan
$189 quarterly

Progesterone is a hormone produced primarily by the ovaries that plays a key role in regulating the menstrual cycle and supporting uterine tissue health. In hormone replacement therapy, bioidentical progesterone is typically paired with estradiol to support balanced endometrial signaling in women with an intact uterus. The sustained-release oral formulation is designed to provide a gradual, steady release of progesterone, which binds to progesterone receptors involved in modulating estrogen's effects on uterine tissue, as well as receptors in the brain associated with calming, sleep-related signaling. EdgeRx prescribes oral sustained-release progesterone as part of a clinician-supervised HRT protocol, typically alongside estradiol, for eligible patients based on individualized lab review.

All online. On your schedule.

No clinic visits. No phone tag. No waiting rooms.

Answer some health questions.

Tell us about your goals, health history, and lifestyle. Licensed providers in all 50 states.

Get your treatment plan.

A licensed doctor reviews your info and prescribes a plan built for your body — not the average patient.

Delivered privately.

Your medication is made at a licensed pharmacy and shipped in plain packaging.

Own your edge.

100% online visits and prescriptions. Made at licensed USA pharmacies. GLP-1, peptide, and hormone plans — prescribed by a doctor.

Shipping fees apply. All medications require a prescription from a licensed provider. Compounded medications are not FDA-approved.