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• Targets IGF-1 receptor signaling in muscle and connective tissue
• Supports protein synthesis pathways via PI3K/Akt/mTOR signaling
• Designed for extended biological activity versus native IGF-1
• May help support tissue repair and recovery processes
• Delivered by licensed physicians as an Rx-only option for eligible patients
IGF-1 LR3 is a modified, long-acting analog of insulin-like growth factor 1 (IGF-1), a downstream mediator of growth hormone's effects on tissue. The molecule has been engineered with an amino acid substitution that reduces its binding to IGF-binding proteins, extending its half-life and biological activity compared to native IGF-1. IGF-1 binds to IGF-1 receptors found on muscle, cartilage, and connective tissue, activating intracellular signaling cascades (including the PI3K/Akt/mTOR pathway) involved in protein synthesis and cellular growth and repair processes. As a prescription-only peptide, EdgeRx makes IGF-1 LR3 available exclusively through a clinician-supervised protocol, prescribed by licensed physicians for eligible patients based on individualized clinical assessment.
No clinic visits. No phone tag. No waiting rooms.
Tell us about your goals, health history, and lifestyle. Licensed providers in all 50 states.
Your medication is made at a licensed pharmacy and shipped in plain packaging.
100% online visits and prescriptions. Made at licensed USA pharmacies. GLP-1, peptide, and hormone plans — prescribed by a doctor.
Shipping fees apply. All medications require a prescription from a licensed provider. Compounded medications are not FDA-approved.