Metformin is a biguanide-class medication widely used to support healthy glucose metabolism. It is thought to work primarily by reducing hepatic glucose production and improving peripheral insulin sensitivity, helping cells respond more effectively to insulin's signal to take up glucose from the bloodstream. In a metabolic health protocol, metformin may be prescribed alongside GLP-1 receptor agonist therapy as an adjunct designed to support continued metabolic progress when patients experience a plateau. EdgeRx physicians may prescribe metformin for eligible patients as part of a clinician-supervised, individualized metabolic health plan, always based on lab work and clinical history.